Endocrine Abstracts

Objective: Non-alcoholic fatty liver disease (NAFLD) is considered as a continuum from obesity and metabolic syndrome (MetS). To investigate the cardiovascular prognosis of metabolically healthy NAFLD, this study aimed to evaluate the association between NAFLD with and without MetS and change in coronary artery calcification (CAC).Methods: This is a retrospective longitudinal study of 5,117 subjects without cardiovascular disease who participated in a he...

Background: Urinary metanephrine (MN) and normetanephrine (NMN) are used to detect recurrence of pheochromocytoma during post-operative period. Currently, reference ranges of urinary MN and NMN obtained from healthy individuals are applied to subjects with adrenalectomy. However, studies regarding the property of using reference ranges from healthy subjects in pheochromocytoma subjects with adrenalectomy are limited.Aim: To compare urinary MN and NMN con...

Background/aims: Maternal subclinical hypothyroidism has been reported to be associated with risks of adverse pregnancy outcomes such as fetal loss and possible fetal neurodevelopmental deficit. However, current guidelines seem to overestimate subclinical hypothyroidism in pregnant women in some regions. Therefore, we aim to evaluate trimester-specific reference range of serum TSH for pregnant women in Korea and whether maternal subclinical hypothyroidism affects perinatal out...

Background: Lipoprotein (a) (Lp(a)) is a low-density lipoprotein like particle which has proatherogenic and a prothrombotic properties. Therefore, increased Lp(a) levels have been reported to be associated with a higher cardiovascular risk in numerous studies. However, the association between Lp(a) and metabolic disorders such as diabetes or metabolic syndrome (MetS) is still controversial. This study aimed to examine the association between Lp(a) levels and presence of MetS i...

Background: Recent studies have shown associations of thyroid hormone levels with metabolic syndrome (MetS) among euthyroid individuals, though there have been some inconsistencies. We evaluated the relationships between thyroid hormones and MetS in euthyroid middle-aged subjects in a large cohort.Methods: Retrospective analysis of 13 496 euthyroid middle-aged subjects who participated in comprehensive health examinations was performed. Subjects were gro...